PSL300 Lecture 1
- What is physiology? It is the science of how the body functions. We care more about how
things work rather than where things are i.e the study of anatomy. However, it is
important to know where things are in order to study how they work
PSL300H Lecture 7: Adrenal gland
What regulates the release & what are the functions of
Why are specific steroids synthesized in different regions
of the adrenal cortex?
What are the functions & what regu
PSL300H Lecture 2: Classification of
hormones and control of release
What are some features of hormones?
Case study: Man with hyperglycemia
What are the three main types of hormones?
How are hormones synthesized?
How is hormone rel
PSL300H Lecture 4
Why is calcium critical for normal physiology?
Where is most of your Ca2+?
Which three hormones control plasma Ca2+ levels?
How do hormones correct a calcium deficit?
How is blood phosphate cont
PSL300H Lecture 3
Receptors and Signalling
How do hormones signal?
What characteristics do receptors share?
What are the two main types of receptors?
Plasma membrane receptors
G-protein coupled receptors
PSL300H Lecture 6
What is metabolism?
What are the metabolic processes in the fed/fasted state?
What hormones are produced by the endocrine pancreas?
Insulin (effects and regulation)
Glucagon (effects and reg
PSL300H Lecture 8: Growth, growth
hormone and thyroid hormones
How do bones form and grow?
How does growth hormone bone growth?
Does growth hormone have any other roles?
What regulates growth hormone release?
How are thyroid hormones synth
Human Physiology I (PSL300H)
Dr. Michelle French
Department of Physiology
PSL300H Lecture 1
What is physiology?
What is homeostasis?
Where are hormones produced?
How were many hormones identified?
Right visual hemifield
Left cerebral hemisphere
LGN gets feedback from V1
which alters it response
Incoming info (new info) meets with past experiences
(outter head )
(input from both eyes)
Lecture 2: Female reproductive system
How are oocytes produced?
What are the components of the menstrual cycle?
How is the menstrual cycle regulated?
What is the function of estrogens and progesterone?
How do birth control pills wo
Sex determination and development
The primordial germ cells
Embryonic origin of reproductive organs
How is puberty regulated?
Primordial Germ cells
The primordial germ cells
A totipotent cell
Gives rise to the gametes of males an
cant tell you about where exactly the light came from
get information from very few cones
<- sound, touch, smell
changes in time: retina
Temporal change: phasic cells
ganglion cell activity increases
ganglion cells activity decreases
Reminder: No class on Friday Sept. 20th
Lecture 6 will take place on Monday Sept. 23rd
PSL300H Lecture 5
Water and ion balance
How is water distributed in the body?
How are daily water intake and excretion balanced?
How is urine
PSL300 lecture notes 2
- With reference to the case study from lecture 1:
The principle being demonstrated was homeostasis.
There is a tremendous regulation of blood pressure; the body maintains blood
pressure by involving the nervous, cardiovascular, r
PSL300 lecture notes 4
- Case study from previous lectures:
1. He doesnt have the right processing of insulin; he is secreting proinsulin (it has a Cpeptide) rather than insulin, which isnt as active as insulin. The antibody count seemed
the same because
PSL300 lecture notes 3
- From last lecture regarding how hormones are measured and the amount of hormones in
It turns out that the level of hormones needed to be active is very low in the blood
they can be at very low plasma concentrations (w
PSL lecture notes 8
- Last lecture:
Conns syndrome too much aldosterone so there is a tumor in the glomerulus (part
of adrenal cortex that makes aldosterone); this means that potassium is lost in the
urine and retaining sodium, weakness in muscles, hyper
PSL300 lecture notes 5
- Case study from last time: The PTH levels are higher because of low calcium levels. The
calcitonin levels will be low because there is low calcium in the blood. The cause is a
genetic defect in the calcitriol receptors; although c
PSL300 notes lecture 7
- FINISHING OFF LAST LECTURE:
Diabetics have a problem with insulin secretion and/or signalling. There are two types
of diabetics: Type 1 tends to be found in children who are not overweight. These
children develop an autoimmune di
PSL300H Human Physiology I
Course Syllabus 2013
Course Coordinator: Dr. Christine Wong
Office: Medical Sciences Building room MS3368 Meetings by appointment only
Dr. Michelle French
Dr. Brian Cox
Where does fertilization occur?
What happens after fertilization?
What prevents menses?
What endocrine gland is temporary?
What can go wrong with placenta development?
How is labour triggered?
Why does labour happen too e