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INTRODUCTION
This e-book contains 100 transistor circuits. Th
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Bioelectricity: Why bother?
Direct Impact on Technology
Biochips
Artificial Neural Networks
Eclectronics : The common frame work of electrical
properties used in both brain and silicon.
ULSI
Direct Impact on Medicine
Organizes bodily functions - cont
Propagation in Time and Space
The Wave Equation
Under Passive Conditions (At Rest)
Consider the Wave Equation
Space distribution at an instant in Time
Time distribution at a site in space
Space distribution at an instant in Time
Time distribution at a sit
V_T = L = f(S,T)
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The passive voltage spread in an axon where a current has been injected at x=0.
The inset shows the voltage versus time in three spots
QUESTION #2
[4 Marks]
Consider the parallel conductance model of a patch of neuronal membrane at rest. Derive
mathematical expressions for (a) the Na+/K+ pump current, and (b) the transmembrane voltage.
Start from first principles and state your assumptio
Lipid
Hydrocarbon
Non-polar
Non-polar
Flux
In the various subfields of physics, there exist
two common usages of the term flux, both
with rigorous mathematical frameworks. A
simple and ubiquitous concept throughout
physics and applied mathematics is the
Single Ionic Channels
Each subunit of the K channel has 6 transmembrane segments (S1 through S6).
The S4 segment contains the voltage sensor.
There is a loop between S5 and S6 that, along with S6, lines the conduction pore.
Four of these subunits are asse
This is basically a reductionist approach in trying to understand
the nervous system. We try to understand how the parts-Work.-
'and what they do, in order to understand the system as a whole.
In the case of the brain, we have several tools available, eac
PROPAGATION OF
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(ngap) PROPAGATIOM
oFBIOELECTmmTY
IN A NEURO/V