The next 2 weeks of neuroscience
Dr. Duncan ODell (slides adapted from Dr. Cecile Fradins slides)
Diffusion & Electro-diffusion (week 1)
Wikipedia: Blausen 0315 Diffusion.png
RC circuits & c
Organic Chemistry, Part 3:
C8H18(l) + O 2(g)
Reactions of Alkanes
1) What are the products of the reaction at 298K?
2) Write a balanced chemical equation
3) Predict the signs of H, S and G
4) What type of reaction is shown?
Sample Test 1 Solutions
Oxidation of Alcohols
Primary, Secondary & Tertiary Alcohols
Primary alcohol aldehyde carboxylic acid
R CH OH
Secondary alcohol ketone
R CH2 OH
Oxidation: Addition of an oxygen atom or removal
Selected sections Ch 26 + Ch 11
The chemistry of life and living
The chemistry of carbon compounds
Why is organic chemistry important?
Medical Application: Molecular Imaging
To understand how we interact with
Sample Midterm Questions
1. Consider the reaction, 2 A 3 B + C. Suppose that, at some time, the rate of disappearance
of A is 0.60 M min1. At that time, what are the rates (in M min1) at which B and C appear?
Charge attraction draws molecules together
In organic chemistry, the reactants are generally
Substitution Reactions and
A charged reactant is attracted to a
concentration of the opposite charge within an
Superposition of Two Travelling Waves - Visualization of Displacement vs. Time
In this scenario, you could think of the phase change occurring because of the time delay between two identical waves.
B (m) =
due Feb. 19, 2017 (11:59 pm)
. Alkanes, Functional Groups, and Their Conformations
Organic compounds typically contain atoms in addition to carbon and hydrogen. When a
hydrogen of an organic compound is replaced by an OH, the
iSci 1A24 Winter 2017
due Jan. 30, 2017 (11:59 pm slide under door ABB 234)
1. The rate of a chemical reaction depends on the concentrations of the reactants. Let's
consider the general reaction between A and B:
The dependence of the rea
A Modern Introduction to Programming
Copyright 2014 by Marijn Haverbeke
This work is licensed under a Creative Commons attribution-noncommercial
license (http:/creativecommons.org/licenses/by-nc/3.0/). All code in the
Sample Test 1 Questions
Core Lab (Chemistry): THE RATE OF A CHEMICAL REACTION
The rate of a reaction refers to how fast a given chemical reaction will occur. Consider the
The rate of the reaction can be measured by determining the rate of disappea
The postsynaptic site
Chemical synaptic transmission has directionality
Two large classes of neurotransmitter receptors
Receptor proteins (us.
multimeric) that are themselves
Wrapping up with channels and transporters!
The membrane potential, Vm!
The action potential
Channels are transmembrane (TM) proteins
all TM proteins share certain characteristics !
! hydrophobicity - how strongly amino acid side chains are pushed out
Wrapping up nerve transmission
What Hodgkin & Huxley did
Getting to the synapse
The action potential, from the GHK perspective
RT pK [K ]o + pNa [Na ]o
pK [K ]i + pNa [Na ]i
The Action Potenti
! Ofce hours: !
! ! Wednesday 12:30-14:30!
! By appointment any day 9:00-21:00!
Instructor contact: emails must include ISCI 2A18 in subject !
! line or they may not be read (and wont get answered
Protein Transport and Targe/ng
Fig. 3 A 3D model of synaptic architecture.(A) A section through the synaptic bouton,
indicating 60 proteins.
B G Wilhelm et al. 2014
Published by AAAS
What is the difference between a qualitative
characteristic and a quantitative characteristic?
The genetics of
The influence of the
Module 1: Population genetics
The gene pool
Mechanisms that alter allele frequencies
Applying theory to sickle cell disease
Society and (mis)understanding genetics
As we talk about population geneti
Module 1: Gene to protein
Genotype to phenotype in sickle cell disease
Mendels first principle: the segregation of alleles
Basics of probability and inheritance
Molecular genetics in sickle cell disease
Terminologies: dominant and recessive ar
Lecture 3. Cats are not peas
There are multiple alleles for genes
Multiple genes determine phenotypic traits.
(Dihybrid ratio (9:3:3:1) and modified dihybrid ratios)
Statistical tests of genetic models
Can you always see the phenotype?
Chromosomal theory of inheritance
A collection of studies revealed that genes are
on chromosomes. In fact, multiple genes are
present on each chromosome.
What is a chromosome? How many do we have?
pair of matching
Organic Chemistry Reactions and Analysis Rubric
- 1 mark for each question
Purpose and Procedure
- Reference the lab manual
Observations and Discussion
- Discuss observations in all reactions
- Draw the TLC plates in your lab books
want to learn more about your research. It describes the objectives of the study (i.e., what
hypothesis you were testing or what research ques
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