Types of adverse drug reactions
What is an adverse drug reaction? Who is at higher risk of having these? Why?
o Higher risk
Age children and elderly
Sex women have more ADRs than men, also ADRs may be related to
pregnancy and nurs
o Lifestyle changes
o Most High BP in children can be traced to an identifiable cause
First line therapy for hyperlipidemia?
Which factor(s) determine the type of cholesterol drug to prescribe or the intensity of your
Heart Failure medications
When working a patient up for chest pain, what are some causes (differential diagnoses) of
o Reduced supply
Increased resistance in coronary vessels
Decreased blood volume, hypotension
Decrease in diastolic filling
Pharmacokinetics and pharmacodynamics
How do drugs affect men and women differently?
o Women experience more ADRs than men due to differences in body
composition, pregnancy status and lactation
o Differences in body composition cause differences in drug d
ARBs Drug-drug interactions?
Decreased absorption of ACEIs
Take them 1hr apart
o Losartan and Potassium
Avoid concurrent use with Potassium supplement or potassium-sparing
What is angioede
Spiriva what drug class, when used? Contraindications?
o Primarily for COPD
o Inhaled anti-cholinergic medication
Smooth muscle relaxation
Reduction volume of sputum
o Cat C
o Not for children alone
o Not for acut
Introduction to pharmacology
What is steady state? Half-life? Phase I and II metabolism?
o Steady State
Any condition in which the formation or introduction of substances just
keeps pace with their destruction or removal so that all volumes,
Nicotine replacement therapy
What are signs that someone is going through nicotine withdrawal?
o Craving, nervousness, irritability, impatience, hostility, difficulty concentrating,
increased appetite and weight gain, myalgia, headache, constipation, fati
Aranesp what do we as prescribers monitor and why?
o Aranesp- darbopoetin- an med that acts like erythropoietin, normally produced by
kidneys to stimulate red blood cells in Renal failure this doesnt happen
o Given SQ or IV
Provide either a chemical or physical barrier to sunlight.
Chemical (absorb portions of UV light) PABA & avobenzone are examples
Physical (reflects and scatters UVA and UVB) - contain ingredients like zinc oxide and
Warfarin drugs OK to use with it? What is normally written on prescriptions for this drug?
What kind of monitoring do we do for patients taking low molecular weight heparin?
o Hct and platelets every 2-3 days initially
Who is at risk for developing coronary artery disease? What patient populations? (for example,
are there specific cholesterol levels, blood pressure ranges we should consider, and so on if they
o Patient Populations
If you are to prescribe a medication like flagyl, what patient education must be provided to your
patient to prevent complications from its use? Pg 795.
o Take with food or snack to decrease GI irritation
HIV, TB drugs
Antiretroviral therapy: What are challenges? Several pages
o Medication resistance
o ART failure
o Patient adherence. discontinuation and interruption of medications
Decreased quality of life due to side-effects
What are goals of the
Vaccines study guide
What are vaccines given routinely to patients?
o Live Attenuated
MMR- Measles, Mumps, Rubella
BCG- Bacillus Calmette-Guerin
Live Attenuated Influenza Vacc
Types of medications? Table 18-1 pg 418, Mechanism of action? pg 416
MOA: inhibits clotting factor X
MOA: potentiates acty of antithrombi n III and inactivates clotting factors Xa and
Gout options for treatment? Mechanism of action of the various gout medications. Pg 802
o Antigout Drugs - reduce the inflammatory process or prevent the synthesis of uric acid
o Acts directly on purine metabolism
Hyperlipidemia what are the various drug classes we use to treat this condition? From Video
Statue in lower corner with red muscles and liver
Ex. Lovostatin, atorvastatin, simvastatin etc.
Most prominently effect LDL, also d
Antibiotics study guide
Categories and examples of each? Mechanism of action for each? Pg 691 and onchapter 24
o Beta Lactams
MOA: inhibits biosynthesis of bacterial cell wall
Ex: Penicillin, aminopenicillin (amoxicillin, ampicillin), Penic
Migraine, anti-seizures drugs
Know how to manage migraine disorder. Know the different drugs (Over the counter and
prescription) available for
o migraine management pg 1036-1051
Classic- Migraine with Aura
Common- Migraine without Aura
MAOIs how do they work (mechanism of action)?
o Irreversibly inactivate the enzymes that break down Norepinephrine, Serotonin and
Dopamine leading to increased bioavailability of these neurotransmitters
What are things you must under
Review course outline and teacher/student expectations
Explain the purposes of health assessment.
Make Judgment or diagnosis on the basis of data from various
sources. It is paramount that your assessment be factual and
Review: 2. communicati
Week 5: Ears & Hearing
Nose & Sinuses
Eyes & Vision Assessments
PNUR 126 Fall 2014 CMB/GRB
Mini Performance Test schedule will be posted
Cranial Nerve Assessments Mnemonics (2)
FOR MORE ON CRANIAL NERVES see pages
PN Health Assessment
Week 6: Thorax and Lungs Assessment
PNUR/IEPN 126 Fall 2015 CMB
Suprasternal notch: Hollow U-shaped depression above
sternum below clavicles
Sternum: Breast bone Manubrium, body and xiphoid p
PN Health Assessment
Week 4: Head, Face, Neck, Regional Lymphatics and
Mouth and Throat Assessment
PNUR 126 Fall 2014 CMB/GRB
What is the function
of the lymph nodes?
What are the
drainage patterns of
the lymph nodes?
In all humans, the immune system (especially T cell production) deteriorates with increasing age;
as a result, older individuals usually have less effective immunity, especially cell-mediated
- AIDS is not a single disease, but a syndrome group o