What is cholesterol?
sterol based on steroid nucleus
regulation of membrane fluidity
steroid hormones, bile acids and vit. D
Sources of cholesterol
de novo synthesis
cytosol and ER
Muscle attachment, locomotion and body shape.
Adaptive biological system.
Detects and processes multiple inputs to produce an appropriate
Types of bone
Long Bones (Femur, Humerus)
inflammatory condition of major blood vessels
wall thickening stenosis
coronary heart disease (CHD)
consequence of AS that affects coronary arteries
cardiovascular disease (CVD)
Gross proliferation of leucocytes which crowd into the BM, spleen, LN etc. and
suppress the blood forming apparatus STARTS IN THE BM
Infections due to loss of functional leucocyt
Definition: Solid tumour of lymphocytes, often originating in lymph node and
developing in lymphoid system, spleen, bone marrow, blood and other organs.
Extra nodal sites skin, bowel, mucosal tissue, blood, brain.
Often painless lump developing a
by the end of this lecture you should be able to:
describe methods by which the initiation and/or progression of
AS may be limited
uptake (plant stanols)
de novo synthesis (statins)
Immune Associated Gastrointestinal Disorders.
Digestive tract: breakdown of food-stuffs to nutrient components to fuel body 3
basic processes of GIT: Processing of food
Absorption of nutrients from small & large intestine Protection from food-born
Ags & p
Digestion : Absorption & Regulation
Absorption of nutrients occurs by:
i) Passive transport simple diffusion along a concentration gradient,
does not require energy eg water, chloride, ascorbic acid, riboflavin.
ii) Active transport involving specif