Chapter 1 Immunology
1. Vaccination programs have eliminated all but which of the following childhood diseases in many
a. All have been drastically reduced: Measles, Mumps, Chickenpox, Polio
2. Pathogens that enter cells and take over cellular
Chapter 9 Immunology
1. The altered peptide model of positive selection states that positive and negative selection:
a. are mediated by different peptides.
2. As double positive cells in the thymus acquire specific identity, they up-regulate genes for lin
Chapter 10 Immunology
1. Distinct from the conventional, or B-2 B cells are the B-1 B cells, which arise from a separate
lineage and produce what are called _ (2 words).
a. natural antibodies
2. Checkpoint 2 in B-cell development:
a. requires a productive
Chapter 16 Immunology
1. One aspect of tolerance is negative selection in the primary lymphoid organs, which is described
as _ tolerance.
2. One of the most common autoimmune disorders is when antibodies target insulin-producing
cells in _ (two
Chapter 2 Immunology
1. Hematopoietic stem cells, like all other stem cells, are characterized by their capacity for
2. Immature T cells as referred to as _.
3. Immune-cell traffic through tissues and lymph nodes i
Chapter 15 Immunology
1. Derived from the Greek phrase meaning "against protection," _ is an
abreaction of the immune system that can result in death.
2. Since accumulation of immune complexes can lead to problems, defects in _ are
Chapter 3 Immunology
1. An event, such as activation of transcription, which is many steps removed from receptor ligand
interaction is known as _.
2. Both the variable and constant regions of the T-cell receptor contain _ (2
Chapter 18 Immunology
1. Inherited immunodeficiencies are termed _.
2. Immunodeficiencies that are acquired during the lifetime of a patient are termed
3. A large number of primary immunodeficiencies are _, meaning they involve
Chapter 6 Immunology
1. The pathway of complement activation that depends on specific antibody binding to targets is
known as the _ pathway.
2. The relative instability of complement proteins on membranes can be regarded as a form of
Chapter 11 Immunology
1. Activation of T cells, in addition to engagement of the T-cell receptor, requires
_ (1 or 2 words).
2. In the absence of antigen, memory T cells can persist at least for months and probably for
Chapter 20 Immunology
1. Immunoprecipitation can be used, gently, to isolate molecules that associate with the antigen in
a process known as _(1 word with a hyphen).
2. A refinement in microscopy that restricts fluorescence to th
Chapter 7 Immunology
1. In addition to variable region gene segments and constant region gene segments, heavy and
light chains also have _ gene segments.
2. TdT is the abbreviation for terminal transferase, an enzyme that:
a. inserts nucleotide
Immunology Chapter 4
1. When a cytokine has different effects on different target cells, it is known as
2. Proteins that inhibit the binding of cytokines are known as _.
3. When two distinct cytokines mediate similar functi
Chapter 8 Immunology
1. MHC class I molecules are comprised of two polypeptides, a large one containing three domains
and a smaller one known as _.
2. Endogenous peptides are generated by the _ and loaded onto MHC class I.
Chapter 5 Immunology
1. In the innate immune system, PAMPs (pathogen associated molecular patterns) are recognized
by _ (3 words).
a. pattern recognition receptors
2. Signaling through pattern recognition receptors leads to recruitment of adaptor molecule
Chapter 19 Immunology
1. Tumors that have limited growth and do not invade the tissues around them are not cancerous
and are described as _.
2. The process by which a tumor evades the immune response is, reasonably enough, termed
Chapter 13 Immunology
1. The Fc receptor, expressed on most cells of the myeloid lineage, interacts with _.
2. Using MHC + peptide as tracers, researchers have been able to label the complex and then track
cells with which the labeled complex is as
Chapter 14 Immunology
1. Lymphocytes in circulation enter several organs, including the lymph nodes, the thymus, and the
2. The cells of the innate immune system that typically respond first to an infection belong to the
Chapter 12 Immunology
1. T-independent B-cell responses in general are characterized by:
a. low-affinity antibody production.
b. IgM production.
c. polyvalent antigens.
2. The B-Cell Activation, Differentiation, and Memory Generation was developed by Sir
Chapter 17 Immunology
1. In addition to physical barriers, the body also maintains _ barriers such as
2. Parasites are generally considered to include protozoans and _ (1 or 2
3. Using antivenin to
Chapter 10: Human Inheritance
Chromosome Theory of Inheritance: states that genes are located on chromosomes
Locus: the physical location of a gene on a chromosome
Chromosomes are composed of a single DNA molecule and many associate
Chapter 9: Patterns of Inheritance
1. Genes: the basic units of inheritance
segments of DNA that help determine an
organisms inherited characteristics or traits
Mendels experiments with pea
plants suggested that the inherited
Chapter 11: DNA and Genes
1. DNA stores genetic information in a sequence of 4 nucleotides thymine (T), adenine (A), guanine (G), and
2. Genome: all the DNA-based information in the nucleoid region of a prokaryote or in the nucleus of
Genetics and Evolution
Jane Goodall was born April 3rd, 1934. She is now 82 years old, she is
known for her study of chimpanzees, conservation, and animal welfare. She is a
animal rights activist. She created one of
Chapter 16 Quiz
1. How many species have been discovered to date?
2. Describe the morphospecies, phylogenetic and biological species concept
Morphospecies concept can be identified in individuals that are extinct
or living in organism that rep
PCB2610 Genetics and Evolution
Exam 3 Study outline
Exam 3 will be held on Thursday, April 21
Chapters 16, 17, 18, 20
1. Review all in-class quizzes
2. Bring your video notes (Becoming Human: Birth of Humanity)
3. Memorize all vocabulary from the chapters
PCB2610 Genetics and Evolution
Exam 1 Study outline
Exam 1 will be held on Thursday, February 11
Chapters 1, 2, 3, 6.1, 14
1. Review all in-class quizzes
2. Bring your video notes
3. Memorize all vocabulary from the chapters and lecture notes