BME/ChE 259 Problem Set #1 (2010)
1. The oxygen diffusion coefficient in tissue is about 1.1x10 -5 cm2/s. The fluid filtration velocity
is typically 1 m/s.
(a) Assuming that convection and diffusion are equal in this system, how large a distance
between c
BME/CHE 250 Problem Set #7
Due: Thursday, November 18, 2010
(Unless you are presenting your project that week, then it is due the following week.)
1.
Problem 6.2
A new protein has been isolated by molecular biologists. Before they can measure its diffusio
PROBLEM SET #8
Problem 10.1
The reaction of A and B to form C is studied under conditions in which the initial
rate can be accurately measured. The following data are obtained:
Initial Conc of A (M)
1.0
2.0
1.0
Initial Conc of B (M)
1.0
1.0
2.0
Initial Ra
BME/ChE 259 Problem Set #1 (2010)
1. The oxygen diffusion coefficient in tissue is about 1.1x10 -5 cm2/s. The fluid filtration velocity
is typically 1 m/s.
(a) Assuming that convection and diffusion are equal in this system, how large a distance
between c
BME/CHE 259 Problem Set #4
Solutions
1.
Problem 3.1
Derive the relationship between the Strouhal number and the Womersley number.
Solution
The Strouhal number =
and the Womersley number =
Begin with the Womersley number
Using T=1/w and L=2R,
.
and multipl
BME/ChE 259 Transport Phenomena in Biological Systems October 29, 2009
MID-TERM EXAM: CLOSED BOOK AND CLOSED NOTES
(100 points total)
Name: _
Please answer all parts and all questions. Show all your calculations clearly, leaving nothing
to interpretation.
BME/CHE 259 Problem Set #4
Due: October 7, 2010
1.
Problem 3.1
Derive the relationship between the Strouhal number and the Womersley number.
2.
Problem 3.2
Using Poiseuille's law (Equation 2.7.45), show that the friction factor defined in Equation (3.5.6)
BME/ChE 259 Problem Set #3
Due: September 30, 2010
1. Flow Chamber for Adhesion Study
A parallel plate flow chamber is being designed to study the adhesion of leukocytes to
endothelium. The channel width is 2 cm. Determine channel heights that can be used
BME/CHE 250 Problem Set #7
Due: Thursday, November 18, 2010
(Unless you are presenting your project that week, then it is due the following week.)
1.
Problem 6.2
A new protein has been isolated by molecular biologists. Before they can measure its diffusio
BME/CHE 250 Problem Set #8
Due: Thursday, December 9, 2010
Problem 7.2
The permeability across a thin rectangular region of tissue is defined as:
Pi
Ni z
C0 CL
where C0 is the solute concentration in blood, CL is the concentration in the
lymph, and L is
BME/CHE 259 Problem Set #6
Due: October 21, 2010
1.
Problem 5.1
The pressure drop in a curved vessel is affected by the curvature of the vessel. Consider a
Newtonian fluid of density and viscosity flowing at an average velocity v through a
curved segment
BME/CHE 259 Problem Set #5
Due: October 14, 2010
1. Problem 4.5
(a): Application of boundary layer theory to estimate the entrance length for channel
flow.
Developing flow within a channel can be examined with boundary layer theory. Consider
a rectangular
BIM 106 Project
Due March 16, 2012
Drugs can be delivered in a variety of routes, ranging from pills,
ointments, crmes, injections, eyedrops, and many others. Drug delivery
through the skin
BIM 106: BIOTRANSPORT PHENOMENA
Instructor: Professor Kent Leach
Office: 3321 GBSF
E-mail: jkleach@ucdavis.edu
Office hours: Tues 4-5 pm or by appt.
Teaching assistant: Allison Hoch
Grader: Alan Man
1
How do surveyed students spend their time?
3
http:/www
2/1/12
Heart Valves
3-4 cm2
4-6 cm2
Calcified heart valve. Rosenhek et al. (2000) NEJM
www.heartcenteronline.com
1
2/1/12
St. Louis University School of Medicine
www.echobyweb.com
Mark Kittleson, UCD VMTH
Ball and cage valve
Bjork-Shiley valve
Carpentier
3/6/12
Figure 8.1 Examples of porous structures. Upper left, a regular array of cylindrical
pores; upper right, a foam structure; lower left, a granular structure; and lower right, a
fiber matrix. In all examples, the white regions represent void spaces o
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 20, Number 1, 2005
Published online on October 18, 2004; doi: 10.1359/JBMR.041009
2005 American Society for Bone and Mineral Research
Fluid Shear-Induced ATP Secretion Mediates Prostaglandin Release in
MC3T3-E1
Unsteady diffusion
c i, s - c i
Y=
c i,s - c i,0
XD =
Dij t
x1
2
x
n=
x1
Dij
m=
kc x1
Unsteady diffusion
c i, s - c i
Y=
c i,s - c i,0
XD =
Dij t
x
2
1
x
n=
x1
Dij
m=
kc x1
Unsteady diffusion
c i, s - c i
Y=
c i,s - c i,0
XD =
Dij t
x1
2
x
n=
x1
Dij
m=
kc
BME/CHE 259: Transport Phenomenon in Biological Systems
Problem Set #1, Due: September 22, 2011
Reading: Truskey Chapter 1
Problem Solving:
1. The oxygen diffusion coefficient in tissue is about 1.1x10-5 cm2/s. The fluid filtration velocity
is typically 1
1/26/2012
BLOOD COMPOSITION
W hole blood consists of formed/cellular elements and plasma
Formed elements: Red blood cells (RBCs) or erythrocytes
W hite blood cells (WBCs) or leukocytes
Platelets
Plasma consists of: Water (92%)
Plasma proteins (7%)
Othe