Hemoglobin:
Learning Objectives
Describe the basis for small molecules binding to
proteins, and given data determine how much
binding occurs under various conditions
Explain the similarities and differences of oxygen
binding to myoglobin vs hemoglobin
Des
Introduction to Enzymes:
Learning objectives:
Students will be able to:
Explain why enzymes are good biological catalysts
Distinguish between kinetic and thermodynamic spontaneity.
Describe how enzymes recognize their substrates.
Describe how enzymes
A
Chem153A Winter 2016
Midterm #2 Form
Full Name:
Page 2 of 5
1. (22 pts) Below is the catalytic mechanism for an enzyme you have studied.
A. (2 pts) What enzyme catalyzes this
B. (2 pts) What enzyme ctass does
c. (2 pts) what
D. (5 pts)
is
reactionJha I
Midterm Policies
Covers All material before the midterm:
Through Glycolysis
During Lecture
No Calculators
Locations:
Last Names:
A
I
H
Z
Lecture1
(9am-9:50)
Last Names:
Haines A2
CS76
A Ho
Hu Z
LA Review session: Fri 7-9pm Location: TBD
Lecture 2
(1
Enzyme Inhibition:
Learning Outcomes:
Students will be able to:
Understand the different types of enzyme inhibitors:
Know how to determine what type of inhibitor a compound is
Describe how each inhibitor interacts with enzymes
Explain how this inhibit
Protein Structure Investigation
Due: Wed Jan 25th, at 11:59pm:
uploaded to Gradescope.com
Search the Protein databank for structure information
Visualize protein structures in pymol
Analyze secondary structure content
Visualize molecules bound to proteins
Enzymes Quiz
Fri Feb 10th
Enzyme classes:
-no subclasses in quiz, but they will show up on the quiz.
Define Classes
Identify class from a reaction
Enzyme names:
What can you know from the name
Catalytic Mechanisms
Define mechanisms
Explain how a
Chem 153A Winter 2017
Study Guide: Midterm #2
Compounds to know:
glycolysis intermediates: Recognize structure, full name
Carbohydrates: Identify vs glycosidic linkages
Identify whether a structure is oligosaccharides and polysaccharides, glycogen, starch
Catalytic Mechanisms:
Learning Outcomes
Students will be able to:
Describe the different mechanisms enzymes use
to catalyze reactions
Identify the catalytic mechanisms used in a full
enzymatic mechanism
Explain the purpose of the mechanism used.
Purpos
Carbohydrates and Lipids:
Students will be able to:
Identify the structural differences in carbohydrates
(disaccharides, oligosaccharides, or polysaccharides)
and explain how they lead to functional differences.
Explain how the different physical proper
Introduction to Metabolism
Learning Outcomes:
Students will be able to:
Distinguish between catabolism and anabolism.
Define the term high energy compound in chemical terms.
Identify features common to metabolic pathways and locate these features
withi
Regulation of Glycolysis
Learning Outcomes:
Students will be able to:
Identify the points of regulation in glycolysis and correlate activators and
inhibitors of the reactions with the flow of metabolism.
Characterize far from equilibrium (sometimes call
Aerobic Metabolism: Pyruvate Dehydrogenase
Learning Outcomes:
Students will be able to:
Describe the compartmentation of the central metabolic
pathway and explain the consequences.
Identify the enzymes of pyruvate dehydrogenase.
The cofactors involved,
Lipids and Membranes
Greek: lipos, fat
Chemically diverse set of molecules
that are insoluble in water
Lipids and Biological Membranes:
Learning Objectives
Know the structure and basic function of the major categories of
lipids
Explain how the different
Protein Structure:
Learning Objectives
Know the general types of protein structures and
cofactors
Diagram the stereochemistry of the peptide bond
Explain the structure of the peptide bond, and its
consequences for protein folding
Identify the four dif
Amino Acids and Peptides
Learning Objectives
Know the characteristics used to categorize amino
acids, and which category each is in.
Know the three letter codes, and 1 letter codes of all
the amino acids
Be able to draw the structures of all the amino
Glycolysis
Learning Objectives:
Explain why each step of glycolysis is necessary
Distinguish between G and Go
Discuss what is meant by the term far from equilibrium
reactions (sometimes called irreversible reactions), and
discuss it in terms of specifi
Introduction to Enzymes:
Learning objectives:
Explain why enzymes are good biological
catalysts
Distinguish between kinetic and thermodynamic
spontaneity.
Understand how enzymes recognize their
substrates.
Know and be able to identify the different classe
Non-Covalent Interactions
Learning Objectives:
Describe the structure of water, and its
consequence for the physical characteristics of
water.
Discuss how the physical characteristics of water
affect biological molecules.
Identify the physical basis of no
Amino Acids Quiz
Monday Oct 13th
Identify an amino acid:
Full name
Three letter code
1 letter code
Net Charge at pH 7.4
List Categories
which aa are in each one
Chemistry review:
Learning objectives:
Understand steady state, and distinguish it from
equili
Oxidative Phosphorylation
Learning Objectives:
Know how substrates for oxidative phosphorylation get into the mitochondria.
Understand the chemiosmotic hypothesis and explain the evidence for it.
Describe the effects of uncouplers on intact mitochondri
Citric Acid Cycle (CAC)
AKA:
Tricarboxylic Acid (TCA) Cycle
and Krebs Cycle
Learning Objectives :
For each step of the TCA cycle, Know:
What we get out of it.
Thermodynamics
Be able to follow where the carbons of Glucose end up in the
CAC, or where ea
Oxidative Phosphorylation
Learning Objectives:
Know how substrates for oxidative phosphorylation get
into the mitochondria.
Understand the chemiosmotic hypothesis and be able to
explain the evidence that supports it.
Describe the effects of uncouplers
Introduction to Metabolism
Learning Outcomes:
Students will be able to:
Distinguish between catabolism and anabolism.
Define the term high energy compound in chemical terms.
Identify features common to metabolic pathways and locate
these features withi
Problem Set 1
BILD1 Fall 2015
1) Using water as an example, explain what a polar molecule is. Draw a stick
diagram, label which atoms have a partial positive charge and a partial negative
charge.
Problem Set 2
BILD1 Fall 2015
NOTE: Not all of this material will be on midterm #1
1) Answer each of the questions below using only the following terms.
Nucleus, Mitochondria, Golgi, Endoplasmic Reticulum, Lysosome, Plasma Membrane,
Ribosome, Peroxisome,
Aluminum 6061-T6; 6061-T651
Subcategory: 6000 Series Aluminum Alloy; Aluminum Alloy; Metal; Nonferrous Metal
Close Analogs:
Composition Notes:
Aluminum content reported is calculated as remainder.
Composition information provided by the Aluminum Associati
