Alleles of the same gene.
Many genes influencing/contributing to one trait
More than one gene involved in expression of a trait.
How many genes?
How do they interact?
Allelic Interactions (one gene)
Genomes & Genomics
Traditional Whole Genome Shotgun Sequencing
Make genomic libraries
Use microbes for cloning DNA pieces
Ex.) E. coli or yeast
NEXT GENERATION Whole Genome Shotgun Sequencing
Genomic DNA is cut int
Digestion and Homeostasis Notes
Teeth Types Incisors - Snipping
Canines - Stabbing, Tearing
Premolars - Shearing
Molars - Crushing and Grinding
teeth come from skin
The ARCHED palate separates the air and
Signal peptide - one continuous sequence, on either N or C terminus
Signal patch - sequence broken into multiple pieces, can only be recognized
when the protein is folded in 3D conformation.
Signal sequence must be necessary and spec
Mendelian Genetics: Patterns of Inheritance
Using a phenotype to determine the genes
Using genetic information to pick candidate sequences and see what results
from mutations to the sequence.
Plasmids can hold genes for mating, antibiotic resistance (killing other
Auxotrophs (variants of WT) - Cannot synthesize all needed nutrients; thus,
they need those nutrients supplemented in the media.