BME136 ENGINEERING OPTICS FOR MEDICAL APPLICATIONS (Elective foe BME) Catalog Data: BME136 Engineering Optics for Medical Applications (Credit Units: 4) Fundamentals of optical systems design, integration, and analysis used in biomedical optics. Design co
Engineering Medical Optics
BME136/251 Winter 2017
Monday/Wednesday 2:00-3:20 p.m.
Beckman Laser Institute Library, MSTB 214 (lab)
Teaching Assistants (Office hours: Every Tuesday at 2pm
outside of the BLI library)
Jue Hou (jueh@uci.edu)
Jessie Lam (jhlam@
Engineering Medical Optics
BME136/251 Winter 2017
Monday/Wednesday 2:00-3:20 p.m.
Beckman Laser Institute Library, MSTB 214 (lab)
Teaching Assistants (Office hours: Every Tuesday at
2pm outside of the BLI library)
Jue Hou (jueh@uci.edu)
Jesse Lam (jhlam@u
Gaussian Laser Beams
LASER BEAM CALCULATION
ENTER THE INITIAL BEAM DIAMETER AT WAIST 1 (w1), THE WAVELENGTH OF LIGHT ,
THE FOCAL LENGTH OF THE LENS (f) AND THE DISTANCE OF THE WAIST FROM THAT
LENS (d1).
Enter w1
1.5 . 10
w0
3
Meters
w0
w0
to get radius fo
Solutions to homework 2
Problem 1
Based on slides 24 Reflection and Refraction
We consider the s polarization.
A1
,
A2
and
A3
are the magnitude of the EM
wave. Then
A 1 sin ( i ) + A2 sin ( i )= A 3 cos ( t )
A 1 cos ( i ) A 2 cos ( i )= A 3 sin (t )
From
1. Pump: Provides the energy to move the electrons from ground state to excited state and fulfil
the population inversion
Gain medium: The optical gain in the laser cavity when pumped.
Feedback: Provide the seed for stimulated emission.
The pump will make
Homework 3 Solution
Problem 1
(a) The core is always the material with the higher index, otherwise we cannot establish the
conditions of total internal reflection. Core = 1.45, Cladding = 1.436.
(b) NAstep= SQRT(nc 2+ nf 2) = 0.201
NA = n outside sin(max)
HW 1- Sources and Detectors - Solution
1. (a) Describe the characteristics of good and poor temporal coherence as well as spatial coherence
from a light source.
Refer 1/7 lecture slides 11 through 16.
(b) Show that =
, where is the change in frequency or
Homework2#3
Homework
Due 01/23/2013
Due Date: Date: 2/1/2016
Wave Optics
1. (a) An unpolarized plane wave of light with wave number k, and angular frequency is traveling in
the positive z direction. It passes through a linear polarizer orientated at /4 wi
Homework 2 - Solution
Wave Optics
= =
3
(a) Long coherence length, like in the case of a HeNe, equates to poor resolution.
(b) Lateral resolution determined by beam waist w0 = 4 /*f/D. So , f, and D. Smaller beam
waist means more a lot more scanning time
1. Briefly explain how the 4 models describe the light and compare their main features and limitations.
2. In an experiment, you use a Thorlab photodetector (FDS10X10) to monitor the power fluctuation of
a 532nm LED. The configuration is as below.
a. Labe
Cerebral hemodynamics during anesthesia
Phenylephrine
Lingzhong Meng
L. Meng, et al. Brit J.
Anes, 107, 209 (2011)
ISS Oxiplex
(Frequency Domain)
<65% ~3-4 minutes/bolus
Ephedrine
Tissue Oxygenation during Exercise
Hamamatsu TRS 20
Time Domain-NIRS
Gaussian Laser Beams
LASER BEAM CALCULATION
ENTER THE INITIAL BEAM DIAMETER AT WAIST 1 (w1), THE WAVELENGTH OF LIGHT ,
THE FOCAL LENGTH OF THE LENS (f) AND THE DISTANCE OF THE WAIST FROM THAT
LENS (d1).
Enter w1
1.5 . 10
w0
3
Meters
w0
w0
to get radius fo
Homework 4 Solutions
1.
2.
Solution in lecture notes.
3.
4. a.
b.
c.
(
)
=
.
= 50
= (1 ) = (1 0.98)220 = 4.4
=
= 0.2273
5. a. It is modulated in time or space.
b. It allows us to decouple the absorption coefficient from the scattering coefficient.
c. Amp
GEOMETRICAL OPTICS
Lectures 1/13 & 1/15
Engineering Optics for Medical Applications
Albert Cerussi
acerussi@uci.edu
824-8838
Beckman Laser Institute
Module Goal
Learn enough basic optics to communicate
how to couple light from point A to point B
couple la
Homework 2 Solution
Problem 1
(a) The core is always the material with the higher index, otherwise we cannot establish the
conditions of total internal reflection. Core = 1.45, Cladding = 1.436.
(b) NAstep= SQRT(nc 2+ nf 2) = 0.201
NA = n outside sin(max)
Instrumentation for Optical
Spectroscopy
Rolf B Saager, PhD
(on behalf of Anthony J Durkin, PhD)
BME 136
2/10/14
What do you need to do Optical Spectroscopy ?
Light Source
Laser
LEDs
Broadband source
Wavelength selection
monochromator
narrowband fi
Photonic Devices:
Detectors"
Photon
Source
Light -Tissue
Interaction
Optical System for
Light Delivery and Collection
Photon
Detector
Chapter 13 in Hecht
Optical Detection
Transduction: convert radiant (optical) power
into electrical signal
Pho
Principles and Applications of
Optical Spectroscopy
Anthony J. Durkin and Bruce Tromberg
Objectives
Spectroscopy 1
What is it ?
Energy levels
Fundamental processes
Absorption, Fluorescence, Scattering
Spectroscopy 2
What are the primary components
GEOMETRICAL OPTICS
Engineering Optics for Medical Applications
Albert Cerussi
acerussi@uci.edu
824-8838
Beckman Laser Institute
My Goal for You: Navigate Catalogs
Review
Basic refraction: Snells Law
Thin lens equation
optics conventions
different types of
Tissue Optics and Functional
Imaging
http:/www.virtualphotonics.org/
Medical Imaging
Mainstream Modalities
MR, X-ray, Nuclear, US(Optical)
Medical Optics
Standard of Care
Eye
Endoscopy
Technology to Patient:
Low Cost, Low Barriers
Contrast across spatia
Homework 2
Homework 3
2
Due Date: 01/30/2013
Due Date: 01/25/2016
01/25/2016
Geometrical Optics
Problem 1
Say that we take an optical fiber with indices of refraction of 1.450 and 1.436, with a core
radius of a=50m.
(a) Which index is the core and which i