Organic I Laboratory
Activity #3: Recrystallization and Melting Point of Benzoic Acid
Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic
acid. Crude benzoic acid mixture, containing cellulose and methyl orange, wa
The Grignard Synthesis of Triphenylmethanol
Experimental Outline: The goal of this experiment was to synthesize, purify and characterize the
product of a Grignard reaction: the alcohol, triphenylmethanol. The Grignard reagent, phenyl magnesium
Molecular Modeling Assignment
1) Find the conformation minimum energy (kcal/mol) of the following isomers:
a. Axial-methylcyclohexane: 8.683
b. Equatorial-methylcyclohexane: 6.902
What is the energy difference between the two isomers?
Qualitative Analysis: The Identification of Unknowns
The goal of this experiment was to separate and find the identity of a liquid and solid in an
unknown compound through various qualitative techniques that determined the me
1. The Chipping Sparrow number seemed to be high for the first 3 years this experiment
was run, but then there was a sudden drop in the numbers during the 4th year. This drop
remained constant for the next 5 years until ther
1. Native tree species will have more damage from insects and pathogens than exotic
species because native species have more natural enemies than the exotic species.
2. From the data, the graph shows that there is no clear pattern between the
o There is no title.
o The best fit line is not accurate.
o The numbers used in the slope calculation are incorrect.
o There is no title.
o The axes are numbered incorrectly and are not labeled.
o The axes are scaled
a. One important goal of Part B of this experiment is to determine if I2 is more
soluble in water or kerosene.
b. Observing the color change in Part B of this experiment can help achieve the goal
of determining if I2 is more solu
a) Transmitted light is light that is being passed on or through an
object. Absorbed light is light that is being taken up or absorbed by
the object. Percent transmission is the fraction of light that passes
through an object at
The name of Fe(CN)63- is ferricyanide.
The oxidation state of Fe in this ion is +3.
Kc = 9.1 x 1041
CN- acts as a Lewis base and donates electrons while Fe3+ acts as a Lewis acid
and accepts electrons.
a) moles =
1) - A strong acid is a strong electrolyte that will completely ionize in water while a weak acid is
a weak electrolyte that only partially ionizes in water.
- A Bronsted-Lowry base is a substance that accepts a hydronium while an A
a) When preparing a standard solution, the solute of the solution is of a known
concentration. When standardizing a solution, the solute of the solution is of an
b) A volumetric flask is used when preparing
1) The freezing point of a liquid is the temperature in which the liquid becomes a
solid. The phases include a liquid turning into a solid.
a) A solute, such as NaCl, affects the freezing point of a solution by lowering it
Harris: Quantitative Chemical Analysis, Eight Edition
CHAPTER 11: Opener
Ion Channels in Cell Membrane
Chapter 11.0 Ion Channels in Cell Membrane
- Gramicidine A is made of 15 amino acids wound into a helix with a 0.4 nm- diam
Introduction to NMR Spectroscopy Laboratory Assignment
1. Rf values do not provide definite proof because there is still the possibility of two
different compounds to have identical Rf values.
2. A) Spectrum A : caffeine
Spectrum B : Aspirin
Spectrum C :
Structural Probing of a Protein
Phosphatase 2A Network by Chemical
Cross-Linking and Mass Spectrometry
Herzog et al. Science 2012, 337:1348-52
April 12, 2016
Most cellular processes are not controlled or regulated by a single
Theory of Chromatography
A chromatogram is a graph showing the
detector response as a function of elution
The retention time, tR, for each component
is the time needed after injection of the
mixture until that component reaches th
Principles of Instrumental
Gas Chromatography (GC): vaporized analytes (solutes) are partitioned
between a mobile gaseous phase and a liquid or a solid stationary phase
held in a column. The mobile phase doe
Understand how to choose optimal mobile phases
Examine relationships between various separation parameters
and efficiency in RPC
Examine other retention mechanisms encountered in HPLC
Cotton HILIC SPE Microtips
for Microscale Purification
of Glycans and
Maurice H. J. Selman, Mahdi Hemayatkar, Andre M.
Deelder, & Manfred Wuhrer. (2011). Anal. Chem.,
83, 2492-2499. doi: dx.doi.org/10.1021/ac1027116
Review factors that control equilibrium processes such as
Discuss predicting distributions of solutes in different
Introduce concepts of diffusion & molecular transport
CHEM 2220: Chemical Separa
Synergistic Effect of Graphene
Oxide/MWCNT Films in Laser
Spectrometry of Small Molecules and
Young-Kwan Kim, Hee-Kyung Na, Sul-Jin Kwack, Soo-Ryoon Ryoo,
Youngmi Lee, Seunghee Hong, Sungwoo Hong, Yong Jeong, and
Categorize major types of chromatographic methods
Become familiar with processes of sample retention
Understand mechanisms of band broadening
Gain perspective on plate theory and the relevance of rate
Examine how thermodynamics of equilibria
Closed & open systems
Equilibrium in presence of external fields
Thermodynamics & Equilibrium
Gain understanding of mass spectrometry background &
Explore various ion sources and mechanisms of ion generation
Survey various mass analyzers and mechanisms of mass
separation & detection
Become familiar with theory governing ion mobility
Get an idea of various ion mobility instrument configurations &