Biol. 1311 9/20/06 Translation ala E. coli New piece of central dogma (Fig 15.10) in Blue box today The translator is the ribosome (Fig 16.13a) This structure is far bigger than the polymerases Consists of RNA and protein Ribosome makes the chain, but it
Study Guide for Biology I. Natural Selection: A. Darwins Theory of Evolution by Natural Selection 1. Individuals within populations are variable 2. This variation is at east in part, heritable a. Darwin did not understand genetics 3. In every generation,
Biol. 1311 9/18/06 Transcription ala E. coli Here we are again at the central dogma (Fig 15.10) RNA polymerase starts in a regulated place and goes only one direction (16-1) DNA is only exposed in short patches (no eq. Fig) And there is a defined stopping
Biol. 1311 9/15/06 Basics of nucleic acid coding of protein sequence Nucleic acids as information carriers All evolutionary change incorporates a change in nucleic acid sequences A very brief review of nucleic acids (Fig 4.1) Polymerization looks similar
Biol. 1311 9/13/06 - Hemoglobins commute The red arrows are not diffusion (fig 44-1) Open versus closed circulatory systems Open systems have low flow and may not even be primarily there for gas exchange Closed systems have high flow rates and are always
Biol. 1311 9/11/06 Hemoglobins work environment
Please note where the Hb doesnt go (fig 44.1) Organisms have built structures to make use of hemoglobin warts and all Relative to O2, Hb is big; 32 daltons versus 68,000 O2 can get through a membrane (in fac
Biol. 1311 9/8/06 What hemoglobin does What it means to bind oxygen As you reasoned out: It isnt a shield but a trap The trap size is limited: if O2 continues to increase, it fails Conclusion: the protection is transient What happens when threat is gone?
Biol. 1311 9/6/06 Protein structure/function Most metabolic functions depends on protein structure 20 amino acids in an almost infinite number of possible sequences Linear sequence is a polypeptide; when folded into 3D shape it is a protein 20 amino acids
Biol. 1311 9/1/06 Know your macromolecules What biology needs to be attentive to about chemistry (for now): Covalent bonds keeping in mind that these are made and broken by enzymes, not unmediated chemical reactions; Ions, but not ionic bonds Lots of hydr
Biol. 1311 8/30/06 why hemoglobins everywhere? Where we are on the concept map Vitreoscilla and its hemoglobin: Why should it be a surprise that a bacterium has this molecule? Bacterium with scale bar (fig 7-1) Same question for yeast, but with scale bar.
Biol. 1311 8/28/06 A diversity tour Biological Diversity as seen through Hemoglobin Phylogeny of protein sequences for diverse hemoglobins Note that this phylogeny brings together diverse organisms And what is a flavo-hemoglobin? The phylogeny of everythi
Biol.1311 9/29/2006 explaining the last of Hardison through gene regulation
Treating bases as characters (no eq. figure) Alternative to Fig. 26.4 How would you figure out which was the ancestral state? Add in a second base as a second character; 7 total c
Biol. 1311 9/27/06 Phylogeny principles A phylogeny of hemoglobins just what does it mean and what are the rules to create one? Phylogenies and the history a species or a gene What patterns can be discerned as species appeared and disappeared over the cou
Biol. 1311 9/25/06 An old globin does new tricks Finally we get back to hemoglobin specific information A preview of transcription in eukaryotes (Fig 18.1) DNA is mostly tightly packed and inaccessible (Fig 18.2) Packing is dynamically regulated (Fig. 18.
Biol. 1311 9/22/06 Translation and review There are 3 possible stop codons (fig 15.8) Three ways to recruit in. Termination (fig 16.17) Releasing factor is actually in 2 pieces Time to review Some names and placed you need to keep straight There are names
BIOL 1311 Global Carbon Cycle Study Guide Fall 2006 Use this guide to assist you in your study of the material covered in the global carbon cycle module. Keep in mind, however, that it is not an exhaustive review of the material covered. To assist you in