Carbonyl oxygen and
amide nitrogen that
make up the peptide
bond are electronegative.
A small peptide of five amino acids
peptide: short chain of amino acids (2-30 residues).
polypeptide: longer chain (up to 4000).
protein: a poly
Post Translational Modifications on Proteins:
A) Chemical modifications to proteins (i.e., the
Usually occur during/after protein synthesis
CH3 C R
can occur on the very beginning amide group of the
peptide chain (next s
Changing gears again: Understanding pH
The concentration of the hydrogen ion
(a.k.a. proton or H+) in solution.
(Actually, H+ exists as H3O+, the hydronium ion.)
Written as [H+]
Dissociation of the water molecule:
H+ + -OH
Forward reaction is very