Sample Final STA2023- Fall 2007 Note: For each hypothesis test: Define Ho and Ha, R.R., Test Statistic, Decision and Conclusion. Decision will be Reject Ho or Do not reject Ho and Conclusion is in the words of the problem. 1. The following data (rand
Stat 516
Homework 5
Solutions
1. Consider conducting m hypothesis tests. Let V denote the number of type I errors. Let R denote the number
of rejected null hypotheses. Let Q = V /R if R > 0, and let Q = 0 if R = 0. Let (0, 1) be xed. By
denition, a method
Stat 516
1.
Homework 3
Solutions
(a) (5 points) Expression data were simulated for an experiment involving g = 10, 000 genes and
two treatment groups with ve independent experimental units in each treatment group. Gene2
2
specic variances 1 , . . . , g we
Stat 516
Homework 2
Solutions
1. See handwritten notes at the end of these solutions.
2. Cut and paste the matrix of numbers to a text le. I saved that le as affypixel.txt. Open R and set the
working directory to the directory containing the le. For examp
Stat 516
1.
Homework 1
Solutions
(a) GAUUACACGUGCCUUGGA
(b) asp tyr thr cys gly
(c) The amino acid cys would change to the stop codon. Thus, we would end up with the sequence asp
tyr thr.
2. See slide 9 of slide set number 3.
3. The notation calls for one
Name: _
Statistics 516
Exam 1
March 3, 2010
1. Suppose a test for differential expression is conducted for each of 100 genes. The following
table provides information about the observed p-values.
Range
Number of p-values
[0.0-0.1]
42
(0.1-0.2]
10
(0.2-0.3
Central Dogma
Basic Biology Related to
Technology for Measuring
Gene Expression
DNA contains genes that code for proteins.
DNA
(transcription)
1/11/2011
RNA
Copyright 2011 Dan Nettleton
(translation)
protein
Proteins perform essential biological functions
Sample Final Answers STA2023- Fall 2007 1. Weights: (20.2, 15.6, 12.9, 14.2, 16.7, 15.0) a) X 15.77 s= 2.52 b) Ho: = 15 oz. Ha: > 15 oz. T.S. t = 0.7485 compared to t of 1.476, do not reject Ho, conclude that you do not have enough evidence to say
STAT 516
HW6
Solutions
1. Answers vary.
2. a)
b)
c)
d)
1
3. Consider the following "data" to be clustered using a variety of methods described below.
10
20
40
80
85
121
160
168
195
For each part of the problem, assume that Euclidean distance will be used