Joint formation (continued) Wnt14 GDF5
Normal wing Wnt14 injected
Wnt14 inhibits Sox9, the inducer of Col2a1.
Joint Formation (again)
This suppresses chondrocyte formation and induces GDF5 GDF5 is required fo
Building blocks are more reduced than the precursor metabolites
1. True 2. False
Group study guides
MCB 3023, Fall 2007 Lecture 14 Chapter 7 Bi Ch t 7:Biosynthesis -Pathways th i P th to buil
Development of Vertebrate Limbs
Skeletal Pattern of the Chick Wing
Limb Bud Formation
Outgrowth and patterning of mouse limb buds
Martin, IJDB, 34:323-336.
Limb buds develop from lateral plate mesoderm (
The Genetic Toolkit for Development
What is the genetic toolkit?
Subset of genes in the genome used to form & pattern the body. Two classes of genes have the most global & profound effects: a) Transcription factors: regulate expression of other ge
Development of the Central Nervous System
Some key definitions. Epithelial cells are tightly connected to one another in a contiguous sheet or tube. They rest on an extracellular matrix layer called a basement membrane. Epithelial cells are polarize