7.03 Problem Set 4 Key
1. a. We can think of lac permease activity (from LacY+) and beta-galactosidase activity
(from LacZ+) as reporters for Lac operon expression from the bacterial chromosome and
the F, respectively. In other words, lac permease activit
7.03 Fall 2003
Problem Set #7
1. (a) Let's denote the disease allele as - and the wild-type allele as +. The "grandfather's"
genotype (top row) at the disease locus must be +/-, since not all of his offspring (the
"parents") are affected by
Solutions to Practice Problems for Genetics, Session 3: Pedigrees
In the following human pedigrees, the filled symbols represent the affected individuals. You may assume that the
disease allele is rare and therefore individuals marrying into th
7.03 Fall 2003
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Answer Key Problem Set 5
1. a) Genetic properties of gln2- and gln 3-:
Both are uninducible, as they give decreased glutamine synthetase (GS) activity.
Both are recessive, as mating them with wildtype produces normal GS activity.
Solution for Practice Problem for Recombinant DNA, Session 3: Constructing and
Screening a Recombinant DNA Library
You have isolated many different yeast auxotrophs. You want to make a yeast genomic library so that
you can clone all of the gene
The genes for two human autosomal dominant traits are 10 cM apart (as determined by
In the following pedigrees
with trait 1
the traits are indicated
with trait 2
From these complementation
of each of the ten strains.
You are studying a plant that normally has light blue flo