1) Discuss three possible mechanisms by which DNA replication
could occur and elaborate why a semi conservative mechanism
is most likely employed
2) Diagram the sedimentation patterns of a messelson and stahl
experiment at the end of t
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ask the students to write on a sheet of paper their definition of personality.
Ask a few students to volunteer their definitions of personality.
Highlight how the students definitions are similar to the definition provided by
Larsen and Buss.
The term per
If you wanted to know what a person was like, what
would you do?
How could you learn about a person: observation,
personality tests, experiment, interaction, etc.
Why would you
Aspects of Cellular and Genetic
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Lecture 3 Objectives
Relationship between genes
Diploid- containing both members of each pair of homologous chromosomes, as
exemplified by most somatic cells, diploid cells are produced from diploid parental
cells during mitosis.
Haploid- containing only one member of each pair of
Signal Transduction I
SPS: Figs 15-1, 2
Vocabulary: receptor/hormone/endocrine gland/autocrine/
Cellular Communication and Signal Transduction
Three basic communication strategies to
respond to extracellular signaling molecules
Smart Pages: Ch 2 fig 24; Chapter 11 figs 41, 42, 44, 46, 47, 49, 50
Translation (protein synthesis): Synthesis of proteins in the cytoplasm using the information encoded by an
mRNA. (11.1, 11.8)
Codons: Sequences of three nucleotides (nucleot
consensus sequence: The most common version of a conserved sequence. The TTGACA
sequence of a bacteria promoter (known as the -35 element) is an example of a consensus
frameshift: Mutations in which a single base pair is either added t
BIOB11Summer2011 Chapter 11: Translation and Chapter 12: The Nucleus and Control of Gene Expression
DNA to RNA to Protein
Clear association between genes and proteins was made (one gene = one polypeptide hypothesis)
Do chromosomes participate in p
BIOB11Summer2011 Chapter 12: The Cell Nucleus and the Control of Gene Expression Gene Regulation
A cell only needs a fraction of its genome at any given moment
Producing unnecessary transcripts and proteins is wasteful and expensive
BIOB11Summer2011 Chapter 15: Cell Signalling and Signal Transduction
Cells usually communicate via extracellular messenger molecules
3 types (distances): autocrine, paracrine and endocrine
Autocrine: released from the cell and tak
BIOB11 Lecture 1 - Chromosomes, Heredity, Meiosis and Recombination
Diploid: Containing both members of each pair of homologous chromosomes, seen in most somatic cells. Diploid cells are
produced from diploid parental cells during mitosis. Two
BIOB11Summer2011 Chapter 11: Transcription and Translation Part 1: Transcription
Genes and Proteins
Genes are discrete units of inheritance
Genes physically reside on chromosomes they are pieces of DNA molecule, and they reside at a particular
BIOB11Summer2011 Chapter 10: The Nature of the Gene and the Genome
The Concept of a Gene
Hereditary factors consist of DNA and reside on chromosomes
The collective body of genetic information in an organism
Incomplete 5 end/End replication problem:
The mechanism/action of Telomerase
The consequences of reduced Telomerase activity?
Replication facts in Prokaryote:
DNA repair process
How does DNA Pol detect problem occur?