Examination # 3
BIO358 Spring 2012
The Biology of Being Human
Stony Brook University
BE CAREFUL to use #2 pencil on the scantron sheet, throughout
Read all questions carefully.
There are multiple forms of this exam. BE SURE to u se the scant
"An isolated DNA coding for a BRCA1 polypeptide, said polypeptide having the amino acid sequence set forth in SEQ ID NO:2." (Claim 1 of U.S. Patent No. 5,747,282).
"Product of nature"
a patentable chemical?
On March 29, 2010 a New York federal court ru
Sequencing and analysis of whole genomes
Why sequence a genome?
To define the parts list; to predict:
- number of genes
- description of their products
- function of the gene products?
To reveal the evolutionary history of a genome
Paul M. Bingham and Joanne Souza
BIO 358 EXAM 1
Sample 2 without answers
1. The evolution of non-human animal behavior is vital for us to understand. We looked at one example
that taught us some important lessons playing dead by hog-nosed
Brain can override spinal reflexes (eg. you don't jerk away from
getting a vaccine shot)
Feedback loop = positive feedback (reinforce initial event),
negative feedback (counteracts initial event), or reflex arc (usually a type
Support = muscles maintain your posture when you sit/stand, muscles also stabilize joints, help prevent dislocations.
Mobility = you move because of skeletal muscles. Your guts move because of smooth muscles.
Units of concentration (e.g., molarity)
o Molarity = M = mol solute/L solution
o Molality = m = mol solute/kg solvent
o Normality = N = Molarity of the species that matter.
Cell cycle, cancer & development
22-23 Becoming multicellular
- cell division, the cell cycle and cancer
23-24 Differentiation and patterning.
- early development in Drosophila
Text chapters 17 & 18
Question bank E
Cell division, the cell cycle and cancer
The Human Respiratory System
Air enters the nostrils
passes through the nasopharynx,
the oral pharynx
through the glottis
into the trachea
into the right and left bronchi, which branches and rebranches into
bronchioles, each of which te
SUMMARY OF KEY ISSUES
Wildland-urban interface area, OaklandBerkeley Hills, California 1991
Extreme fire risk created by five year drought, low
humidity, and Diablo winds; highly combustible
natural fuels, inadequate
Week 4 Notes Taking
1. Whats the major natural cause of wildfire?
2. 1871, what are the two major events?
3. What is Arson?
4. Almost all (85%) of wildfires are caused by human activities.
5. Parameters and conditions that commonly lead to wildfir
Genetics, part 2: from genotype to phenotype
Dept. of Neurobiology & Ctr. for Developmental Genetics office: Centers for Molecular Medicine, room 447 (just over the 4th floor bridge from Life Sciences) Hours: drop by any time, or email for
Whoever invents or discovers any new and useful process,
machine, manufacture or composition of matter, or any new
and useful improvement thereof, may obtain a patent.
(Section 101, Title 35, US Code)
An isolated DNA coding for a BRCA1
polypeptide, said p
Table of enzymes
Enzyme Where found
Amylase Mouth and small intestine
Protease Stomach and small intestine
Nuclease Small intestine
Table of digestive tract
Mechanical digestion: chewing
Functions (circulation of oxygen, nutrients, hormones, ions, and fluids; removal of metabolic waste)
o Oxygen delivery to tissues
gets transported to tissues
used in cellular respiration
Cellular respiration makes CO2: ca
Genetics of quantitative and complex traits
- The Mendelian basis for quantitative traits
- Phenotypic and genotypic variation
- Estimates of heritability and the effect of selection
Hartwell: Ch 3.2, 66-68
Ch. 19.3, 674 - 682.
Ch 11.5-6, 387 3
Liquids and gases are fluids.
Density, specific gravity
o Density: =m/V, where is density, m is mass, and V is volume.
o The density of water is water = 1 g/mL = 1 g/cm3 = 1 kg/L.
o Specific gravity is the density of something compared to water.