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central integrin involved in the establishment of virological
synapses, which facilitate efficient cell-to-cell spreading of HIV-1.
The gp160 spike contains binding domains for both CD4 and
The first step in fusion involv
HIV-1 entry, as well as entry of many other retroviruses, has long
been believed to occur exclusively at the plasma membrane.
More recently, however, productive infection by pHindependent, clathrin-dependent endocytosis of H
of progeny virions may be composed of RNA
HIV-1 and SIVcpz, Nef does not inhibit T-cell activation and it has
lost this function. Without this function, T cell depletion is more
between HIV copies (viral load) and CD4 counts over the avera
HIV deaths in 2014.
South Africa (12.51%)
DR Congo (2.17%)
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Some people are
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of genome-damaging reactive oxygen. Thus, Michod et al.
an infected T cell can transmit virus directly to a target T cell via a
virological synapse. Secondly, an antigen presenting cell
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that almost all broadly neutralising antibodies that have so far
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believed to have originated in non-human primates in Westcentral Africa, and are believed to have transferred to humans (a
process known aszoonosis) in the early 20th century.
HIV-1 appears to have originated in southern Cameroon through
Maize (/mez/ MAYZ; Zea mays subsp. mays,
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peoples in Mexico about 10,000 years ago. The six major types
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currently fighting infection.
During viral replication, the integrated
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This article is perfect example of open innovation coupled with customer integration in design
projects, collaborations and informal way of organization. Hartmut Esslinger, a student who
showed the world how an innovation should be approached with collabo
Bug labs and the long tail
The concept of Long tail was first used by Mr. Chris Anderson in wired magazine. Long tail
is one of the useful and unique market strategy used by certain business firms. Long tail
strategy basically means that in
Organizing for innovation at Google
Innovation is a key to success in any type of industry. It keeps the company running and gives
new directions for companys success. The company which lacks in scope for innovation loses its
competitiveness. Creating enc
The case of Given (GI for gastrointestinal, V for video, and EN for endoscopy) is a classic example of
technological innovation combined with entrepreneurial features which achieved substantial
customer base and success in the market. Given
Genzyme was founded in 1981 by group of scientists and it was a biotechnological company which
focuses mainly on producing/inventing drugs for genetically inherited deadly diseases. Soon after the
start it was joined and headed by Henri Ter