Biochemistry is the study of biomolecules. Water has interactive forces and act as a buffer. It is
nearly essential in all reactions. Amino acids form protein. Amino acids and amide bond are very
interesting because they can do anything wi
Hi this lecture will be based on the slide that the professor posted on mycourses because there are a lot of information lacking
from the slides in the booklet. Go on the carbohydrates lecture slides.
What comes on mind when we say carbohydrates?
Exam on Monday will include 30 multiple choice questions.
Kornberg came to conclusion that DNA polymerase I cannot be the only DNA polymerase. They mutated the DNA polymerase I
and expected the DNA replication to stop. However, they did not find
Buffer Problem Set I
What is a buffer? Explain how the following solutes function as buffers:
(a) NaCHO2 and HCHO2
(b) C5H5N and C5H5NHCl
What ratio of lactic acid to sodium lactate is required to give a solution having a pH
Experiment in the late 20s proved that nucleic acid good for storage and transfer of genetic material. It mediates storage and
transfer of genetic material.
a. The discovery of the Transforming Principle:When the scientists proposed the transform
Metabolism and bioenergetics
Professor Armando Jardim
Parasitology building room B1.14 Office Hours Monday and Friday 3-4pm
Advice 15 minutes of biochemistry every day! General rule, if he talked about it in class we are
responsible if he did not we are n
Example of application of biochemistry (Not on the exam)
Nanobots: Considered as some of the building blocks which will have a considerable impact on nanotechnology, for innovation.
Will be used to repair space satellite and kill bad blood cancer one day.
Trans fat are not good for you and can be metabolized but it takes longer and accumulate
Sphingolipids are exciting lipids and if there is any area of lipids which would have a major
breakthrough in the future, that would be sphingol
One property of fatty acid is trans fat and is probably one of the worst thing you could do to your
body. When an unsaturated fatty acid is partially hydrogenated, a trans fat is formed.
There is however some natural sources of trans fat. In natu
A transition state analog resembles the transition state structure of the normal enzyme substrate
Analog- refer to analogy which is something similar
Transition is the intermediate step going into the product. Reactant most unstable form
When enzyme has high affinity then very little substrate is required to saturate enzyme.
K3 +K2- are rate constants of breakdown of ES complex.
When K2+K3 is large, then Km is large too so there is a lot of breakdown. Rate of breakdown is
higher than rate
Lineweaver Burk plot is used to solve, graphically for the rate of enzymatic reaction at an
infinite substrate concentration. It has nothing to do with equilibrium constant which depends on
the concentration of reactants and products.
Which best describes the type of reaction catalyzed by dehydrogenase?
Answer: Oxidation and reduction
Dehydrogenase involves the transfer of a Hydrogen atom.
Which is true for enzyme catalysis?
Answer: They lower the activation en
Hemiacetal can open in linear structure. It is a reducing sugar because it can open and can itself
be oxidized. Disaccharides can be either reducing or non-reducing depending on the bond,
whether it is a hemiacetal or not.
Cellulose metabolism in
Hi, I apologize for posting this lecture so late. I was not sure of something I noted so I wanted to
make sure I was giving you the right information. The lecture is based back on the booklet.
Linear monosaccharides can go from the linear structu
Q: what should we know from the oxidation of glucose? The reaction does not occur
spontaneously. It is an exergonic reaction and is favorable. However being favorable, it does not
say anything about the rate of the reaction.
The driving force of