8. Example of a Prospective Differential Study
J Natl Cancer Inst. 2005 Mar 16;97(6):439-48.
Ethnicity and breast cancer: factors influencing differences in
incidence and outcome.
Chlebowski RT, Chen Z, Anderson GL, Rohan T, Aragaki A, Lane D, Dolan NC, P
PLoS One. 2012;7(3):e33411. Epub 2012 Mar 20.
Cancer Risk in Diabetic Patients Treated with Metformin: A Systematic Review
Noto H, Goto A, Tsujimoto T, Noda M.
Department of Diabetes and Metabolic Medicine, Center Hospital, Natio
Ratios are skewed measures-values of less than 1.0 are compressed (i.e.
yield smaller values progressively) in comparison to values of greater than
1.0, which are expanded (i.e. yield larger values) even though both deviations
form 1.0 mean the same thing
In clinical trials:
When Rx prevents a bad outcome, efficacy of treatment is denoted by RR of <1.0
P= 81/ (615)=0.131
P= 136/ (610)=0.222
TAKE HOME FINAL EXAM QUESTIONS
Answer the following 3 questions with between 800 1000+ words for each. Bring your WORD
PROCESSED answers to the in-class Final Exam next Tuesday, at 2:00 pm. I will NOT accept
an attachment document period! Each is