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Microbiology: An Evolving Science 4th Edition

Microbiology: An Evolving Science (4th Edition)

Book Edition4th Edition
Author(s)Slonczewski
ISBN9780393614039
PublisherW. W. Norton
SubjectBiology

Chapter 24, End of Chapter, Review Questions, Exercise 1

Page 985

Here is a tip:

The immune response adapts in the presence of the new organism.

Explanation

Antigen: A substance that is responsible for initiating the immune response in the body. It is done by determining the markers on the cells. They have the potential to form a bond with a product (antibodies and T cells) of the immune response.

 

Epitope: It is the part of an antigen or a small segment of an antigen that has a capability to interact with the antibodies (antigen specific receptors). They have the potential to elicit an immune response.

 

Hapten: It is a special form of antigen. It is a small molecule that initiates the formation of antibody molecules. The production occurs only when it is conjugated with larger molecules (carrier molecules).

Antigenic determinant: It is a specific site on the surface of an antigen molecule to which a single antibody molecule binds. They are also called hidden antigen because they are located in an unexposed region of the molecule.

Verified Answer

  • Antigen is a substance that elicits the production of antibodies. It stimulates the B-cells to differentiate into antibody-producing plasma cells.
  • Epitope is a small segment of an antigen that is capable of triggering an immune response. It is determined by the specificity of the clonally distributed receptors to which an antigen binds.
  • Hapten is a small molecule that cannot elicit an immune response unless they are bound to a larger carrier molecule.
  • Antigenic determinant is a specific site on the surface of an antigen to which a single antibody molecule binds.
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