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Visualizing Human Biology 5th Edition

Visualizing Human Biology (5th Edition)

Book Edition5th Edition
PublisherJohn Wiley & Sons
Section 18.1: Hormones Are Chemical Messengers
Think Critically
Section 18.2: The Endocrine Glands Secrete Directly into the Bloodstream
Section 18.3: Maintaining Homeostasis Requires Glands, Hormones and Feedback
What a Scientist Sees
Section 18.4: Development Takes Us from Infancy to Adulthood
Ethics and Issues
Concept Check
End of Chapter

Chapter 18, Section 18.1, Think Critically, Exercise 01

Page 385


The hormones that are soluble in lipids are known as lipid-soluble hormones. Steroid hormones such as testosterone and estrogen are examples of lipid-soluble hormones. These hormones easily diffuse through the plasma membrane as the membrane is made of a phospholipid bilayer. Once the hormone enters the cytoplasm, it either binds to the receptors present in the cytoplasm or the nucleoplasm. 

The binding of hormone with its receptor leads to the formation of a hormone-receptor complex that alters the activity of the cell. This complex affects the transcription of genes and either upregulates (increases) or downregulates (decreases) the production of specific proteins. The mRNA (messenger ribonucleic acid) initiated by the hormone leaves the nucleus and directs the formation of a new protein. These new proteins are used by the cell, thereby altering its activity. The hormone-stimulated changes in the cell take a measurable amount of time- more time than is needed to simply alter the function of a protein already in the cell. 

Verified Answer

The biological control for the lipid-soluble hormone lies inside the nucleus.


The receptor for lipid-soluble hormones lies in the cytoplasm or nucleoplasm of the cell.

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