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Organic Chemistry 8th Edition

Organic Chemistry (8th Edition)

Book Edition8th Edition
PublisherCengage Learning
Chapter 24, Section 24.3, Problems, Exercise 24.1
Page 1102

Show how you might prepare each compound by a Heck reaction using methyl 2-propenoate as the starting alkene.



The retro disconnection will help to predict the starting materials. 

 In presence of palladium catalyst C-C coupling takes place. Ortho-iodotoluene will react with methyl acrylate and through Heck coupling reaction highly selective more stable E-conformer will be formed as a major product.

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