| Book Edition | 8th Edition |
| Author(s) | Brown |
| ISBN | 9781305580350 |
| Publisher | Cengage Learning |
| Subject | Chemistry |
Show how you might prepare each compound by a Heck reaction using methyl 2-propenoate as the starting alkene.
The retro disconnection will help to predict the starting materials.
In presence of palladium catalyst C-C coupling takes place. Ortho-iodotoluene will react with methyl acrylate and through Heck coupling reaction highly selective more stable E-conformer will be formed as a major product.
The retro disconnection will help to predict the starting materials. In presence of palladium catalyst, C-C coupling takes place.
1(Z)-1-Iodo-1-hexene will react with methyl acrylate, through Heck coupling reaction selectively from Z-alkene, the 2E, 4Z isomer will be formed as a major product.
