What is the effect of pH on hemoglobin fiber formation in sickle cell anemia?
a) at a higher pH, hemoglobin breaks into alpha beta dimers that form fibers
b) at a lower pH, hemoglobin aggregates to form fibers
c) at a higher pH, surface hydrogen bonds of hemoglobin are disrupted, leading to fiber formation
s) at a lower pH, hemoglobin is unable to release oxygen