EMAE 456
Consider a closed microfluidic cell-culture chamber of dimensions 31 mm 1 mm 120 m (l w h).
View the step-by-step solution to:

Question

Consider a closed microfluidic cell-culture chamber of dimensions 31 mm × 1 mm × 120 μm (l × w × h).

Neutrophils are attached to the floor of this chamber, and cell-culture medium is flowed through the chamber at 0.20 mL/min. The density and viscosity values of the cell-culture medium can be assumed to be the same as water. I. (10 points) Calculate the Reynolds number and comment on the flow conditions inside the chamber. II. (15 points) Calculate the maximum linear velocity (vx) experienced by the cells. For convenience, assume that the velocity changes only as a function of the chamber height. Also, assume that the cells are of a uniform height. Justify the selected height of cells and any additional assumptions made. Hint: Use equations describing pressure-driven flow through a narrow rectangular channel. 

Recently Asked Questions

Why Join Course Hero?

Course Hero has all the homework and study help you need to succeed! We’ve got course-specific notes, study guides, and practice tests along with expert tutors.

-

Educational Resources
  • -

    Study Documents

    Find the best study resources around, tagged to your specific courses. Share your own to gain free Course Hero access.

    Browse Documents
  • -

    Question & Answers

    Get one-on-one homework help from our expert tutors—available online 24/7. Ask your own questions or browse existing Q&A threads. Satisfaction guaranteed!

    Ask a Question
Ask Expert Tutors You can ask 0 bonus questions You can ask 0 questions (0 expire soon) You can ask 0 questions (will expire )
Answers in as fast as 15 minutes