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True or false?

can anyone help me with these questions?

True or false?


 

True

 

False

 

 TPP takes the acetyl group from lipoamide. 

 

True

 

False

 

 TPP is used in PPP and well as pyruvate dehydrogenase. 

 

True

 

False

 

 The Schiff base formed in the transaldolase reaction is a nucleophile. 

 

True

 

False

 

 In the phosphopentose isomerase reaction Ribulose 5-phosphate is converted to Ribose 5-phosphate through an enediolate intermediate 

 

True

 

False

 

 Glucose 6-phospahte dehydrogenase multimerization is not needed for activity. 

 

True

 

False

 

 When Ribose 5-phophate needs are greater than the need for NADPH, Glycolysis and the backwards route of the non-oxidative part of PPP are used. 

 

True

 

False

 

 In the transketolase reaction, the Ylid form of TPP acts as a nucleophile to attack a carbonyl. 

 

True

 

False

 

 Epimerization is when a functional group is "moved" between two different carbons. 

 

True

 

False

True or false?


 

True

 

False

 

 The thiol group of CoA attacks amide bond of acetyllipoamide to create the thioester bond of Acetyl-CoA. 

 

True

 

False

 

 CoA directly attacks pyruvate leading to a loss of CO2

 

True

 

False

 

 Reduced dihydrolipoamide is oxidized by transferring electrons and protons to NADH. 

 

True

 

False

 

 In Succinyl CoA Synthetase an inorganic orthophosphate hydrolyzes the thioester bond of Succinyl CoA to form Succinate. 

 

True

 

False

 

 Lipoamide is covalently linked to E2 of pyruvate dehydrogenase through an thioester bond to the side chain of a Cys residue. 

 

True

 

False

 

 In Citrate Synthase Oxaloacetate is deprotonated to make an enol and oxyanion. 

 

True

 

False

 

 The aconitase reaction isomerizes Citrate to Isocitrate through an Alkene intermediate. 

 

 6-phosphogluconolactonase uses a histidine to deprotonate a water to generate a nucleophilic hydroxyl. 屏幕快照 2018-04-03 上午8.25.22.png屏幕快照 2018-04-03 上午8.25.09.png

屏幕快照 2018-04-03 上午8.25.09.png

True or false? ‘ The thiol group of CoA attacks amide bond of acetyllipoamide to create the thioester bond of Acetyl-CoA.
. CoA directly attacks pyruvate leading to a loss of C02. . Reduced dihydrolipoamide is oxidized by transferring electrons and protons to NADH.
. In Succinyl CoA Synthetase an inorganic orthophosphate hydrolyzes the thioester bond of Succinyl CoA to form Succinate. - Lipoamide is covalently linked to E2 of pyruvate dehydrogenase through an thioester bond to the side chain of a Cys residue.
. In Citrate Synthase Oxaloacetate is deprotonated to make an enol and oxyanion.
. The aconitase reaction isomerizes Citrate to Isocitrate through an Alkene intermediate.

屏幕快照 2018-04-03 上午8.25.22.png

True or false? - TPP takes the acetyl group from lipoamide. . TPP is used in PPP and well as pyruvate dehydrogenase. . The Schiff base formed in the transaldolase reaction is a nucleophile. - In the phosphopentose isomerase reaction Ribulose 5-phosphate is converted to Ribose 5-phosphate through an enediolate intermediate - Glucose 6-phospahte dehydrogenase multimerization is not needed for activity. - When Ribose 5-phophate needs are greater than the need for NADPH, Glycolysis and the backwards route of the non-oxidative part of PPP are used.
- In the transketolase reaction, the Ylid form of TPP acts as a nucleophile to attack a carbonyl. . Epimerization is when a functional group is "moved" between two different carbons. . 6—phosphogluconolactonase uses a histidine to deprotonate a water to generate a nucleophilic hydroxyl.

Top Answer

Answer;  TPP takes the acetyl group from lipoamide. - False TPP is used in PPP and well as pyruvate dehydrogenase. - True... View the full answer

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