View the step-by-step solution to:


 Consider a transmembrane protein that forms a hydrophilic pore across the plasma membrane of a eukaryotic cell,

allowing Na+ to enter the cell when it is activated upon binding a specific ligand on its extracellular side. It is made of five similar transmembrane subunits, each containing a membrane-spanning α helix with hydrophilic amino acid side chains on one surface of the helix and hydrophobic amino acid side chains on the opposite surface. Considering the function of the protein as a channel for Na+ ions to enter the cell, propose a possible arrangement of the seven membrane-spanning α helices in the membrane.

Top Answer

The sevenmembrane-spanning helices of the channel for sodium ions are arranged in such a way that Hydrophobic amino... View the full answer

Sign up to view the full answer

Other Answers

The hydrophilic faces of the five membrane-spanning helices, each... View the full answer

Why Join Course Hero?

Course Hero has all the homework and study help you need to succeed! We’ve got course-specific notes, study guides, and practice tests along with expert tutors.

  • -

    Study Documents

    Find the best study resources around, tagged to your specific courses. Share your own to gain free Course Hero access.

    Browse Documents
  • -

    Question & Answers

    Get one-on-one homework help from our expert tutors—available online 24/7. Ask your own questions or browse existing Q&A threads. Satisfaction guaranteed!

    Ask a Question