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 . Question 19 (1 point) A mutation in a virus arises that changes...

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Question 19 (1 point) A mutation in a virus arises that changes the amino-acid sequence of a viral protein that contains the dominant epitope for the host's CTL mediated immunity. In which of the following situations would this lead to CTL escape? if the affinity of TCR binding is reduced with the new epitope. O If the processing of peptides in the proteasome is affected with the new viral protein. If the efficiency of binding to MHC molecules is reduced with the new epitope. In all of the above situations. Question 20 (1 point) Which of the following could lead to cytotoxic T lymphocyte (CTL) escape? O Impossible, an effective CTL response cannot be avoided Parasites replicating intracellularly in host cells OParasites having a mutation rate of 0 (zero). An amino acid substitution that leads to reduced binding of a parasite's peptide to MHC molecules

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