a. receptor-mediated apoptosis makes use of procaspase-9
b. FADD and TRADD serve as protein kinases in receptor-mediated apoptosis
c. mitochondria-mediated apoptosis makes use of executioner caspases
d. mitochondria-mediated apoptosis involves the movement of cytochrome c into the cytoplasm
e. TNF stimulates mitochondria-mediated apoptosis
Which of the following statements is false?
a. G protein-linked receptors span the plasma membrane seven times, tyrosine kinase-linked receptors span the membrane once per polypeptide chain.
b. G protein-linked receptors form dimmers when activated, tyrosine kinase-linked receptors do not
c. G protein-linked receptors activate adenylate cyclase signaling pathways, tyrosine kinase-linked receptors do not
d. Both G protein-linked receptors and tyrosine kinase-linked receptors are expressed on the plasma membrane
e. Both G protein-linked receptors and tyrosine kinase-linked receptors contain signal sequences that target them to the endoplasmic reticulum
29. Which of the following statements about phospholipase C proteins is false?
a. They are found in the plasma membrane
b. They bind to Gp and to phosphotyrosines on growth factor receptors
c. They induce the formation of diacyl glyercol (DAG) in the plasma membrane but not in the ER
d. They are monomers
e. They complex with co-SMADS to induce activation of SMADs
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