Glutamine synthetase plays a variety of roles in bacterial metabolism. Because glutamine contributes to many metabolic processes, glutamine synthetase is subject to some of the most complex regulation known. Briefly summarize the roles of glutamine synthetase in bacterial metabolism and the means by which it is regulated to respond appropriately to the needs of the
various metabolic processes in which it participates. Do not provide specific details of regulatory processes, but simply identify in general terms how glutamine synthetase is regulated, the molecules responsible for this regulation, and the rationale for each form of regulation.
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