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4) What is the most significant difference between a retroviral vector and an adenoviral vector, when they are used for gene therapy in humans?

4) What is the most significant difference between a retroviral vector and an adenoviral
vector, when they are used for gene therapy in humans?
a) if you use a retroviral vector, the ‘good’ gene being used for gene
therapy will not be integrated into the host genome, reducing the
risk of insertion into a bad location
b) adenoviruses can infect human cells, but retroviruses cannot, so
retroviral vectors are safer
c) retroviruses can infect human cells, but adenoviruses cannot, so
adenoviral vectors are safer
d) if you use an adenoviral vector, the ‘good’ gene being used for gene
therapy will not be integrated into the host genome, reducing the
risk of insertion into a bad location

5) Which of these best describes somatic cell nuclear transfer?
a) reprogramming an adult somatic cell nucleus to behave like an
embryonic cell nucleus by placing it in an enucleated egg
b) causing embryonic stem cells to differentiate into a differentiated cell
type by adding growth factors or other molecules to them in tissue
culture
c) reprogramming an adult somatic cell nucleus to behave like an
embryonic cell nucleus by introducing several transcription factors
into it
d) using retroviral or adenoviral vectors to introduce a normal copy of a
gene into mutant cells
e) transferring a gene from one species into another

6) In an automated machine that performs dideoxy sequencing and capillary
electrophoresis of fluroescently-labelled DNA molecules, which of the following DNA
fragments would run out of the bottom of the capillary first?
a) AT
b) ATCC
c) ATCCCG
d) ATCCCGATTGCACGTT
e) ATCCCGAT
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4) What is the most significant difference between a retroviral vector and an adenoviral
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