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some of the questions on this sample Final exam may ask about material that was not covered this year - you are not be expected to know this content...

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DO NOT TURN OVER THE EXAM UNTIL TOLD TO BEGIN THE EXAM IS DOUBLE SIDED! There are 60 questions - you have 110 minutes , from 1:00 - 2:50 We will deduct 5 points if you fail to turn in your exam when time is over Answer all questions on the machine graded answer sheet (Scantron) PLEASE FOLLOW THESE 4 SIMPLE RULES: 1) Use a number 2 pencil only. 2) Please bubble in your name on the Scantron sheet exactly as it appears on your ID card. Use this format: Last name space first name - do not use any hyphens (Smith-Jones --> Smithjones) 3) Please fill in your exam version number (upper right corner) on the Scantron under ‘special code’ row K ID:A = fill in 0 in row K ID:B = fill in 1 in row K ID:C = fill in 2 in row K ID:D = fill in 3 in row K Failure to follow these rules could mean you get a zero on the exam! You may keep your copy of the exam
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Name: _____________________________ BIOL 302 Final Exam Spring 2010 ID: A 1 Final 2010 Select the single best answer for each question. 1) Which of these does not result in the E2F transcription factor turning on expression of S phase specific genes? a) phosphorylation of Rb by CDK b) destruction of p53 by the proteasome c) binding of growth factor and activation of a signaling pathway d) increased expression of cyclinD gene e) loss-of-function mutations in both copies of Rb 2) A ‘carrier’ for a disease a) is hemizygous for a recessive mutation b) is heterozygous for a recessive mutation c) is homozygous for a dominant mutation d) is homozygous for a recessive mutation e) is heterozygous for a dominant mutation 3) An exploratory expedition to a giant frozen lake present under Antarctica uncovers a bacterial species that has been isolated from the surface for a billion years. It is determined that the genetic information in this organism is encoded by the four bases A, C, G and T, that DNA is transcribed and translated as in other organisms, there are three stop codons, but that the genetic code in this organism is nondegenerate and read in groups of two. Which of these statements is likely also to be true about this organism? a) E. coli would most likely be able to translate mRNAs from this organism b) the tRNAs from this organism would have anticodons of four bases c) 48 codons used by this organism do not encode amino acids d) there are many more codons per amino acid in this organism than in E. coli e) Only 13 of the 20 standard amino acids are used to make proteins in this organism
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