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Spontaneous depurination of DNA occurs at the rate of approximately 3 X 10-9 depurinations per purine per minute, most of which are repaired.

Spontaneous depurination of DNA occurs at the rate of approximately 3 X 10–9 depurinations per purine per minute, most of which are repaired. The genome size of a diploid human cell is approximately 6 X 109 base pairs. Approximately how many spontaneous depurinations must be repaired per day in each cell in your body? How many total depurinations in your body each day?

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