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How would you demonstrate experimentally that the receptor couples to a G protein to regulate cAMP levels?

How would you demonstrate experimentally that the receptor couples to a G protein to regulate cAMP levels? (Note, sequence homology to other known GPCRs is NOT necessarily sufficient to demonstrate that the receptor is a GPCR!)
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How would you demonstrate experimentally that the receptor couples to a G protein to regulate
cAMP levels?
During signal transduction a stimulator or hormone bind to a receptor on cell surface and...

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