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How accurate does a pH calculation need to be?

How accurate does a pH calculation need to be?
Consider a real-life situation in which pH is an important factor, such as the 7.35-7.45 normal pH range of human blood.
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8204946- Chemistry.doc

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As, a bit difference in pH might lead towards greater changes hence; it’s better to calculate pH as
accurately as possible. For instance; a 6.9 pH containing chemical would reflect acidity...

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