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The physician confirms that Mrs. M.'s "new symptoms," as she refers to them, are a result of polypharmacy. She

protests, telling the nurse, "Honey, I've got news for the doctor. I've had to take lots of drugs at the same time all my life. It never bothered me before. Why would it now when I'm even more used to it?" Explain at least three physiologic changes that occur with aging and the way in which these changes affect pharmacokinetics and pharmacodynamics.

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Elderly people are generally physically smaller than they were when they were younger because of a loss of muscle mass. They... View the full answer

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