My main question is how would I use the hasselback equation to determine the degree of ionization for one of the drugs listed? I need an example so I can complete the rest. Also if you could point out what the functional groups of the given drug is.
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The following is a list of drugs. For this assignment, use any resources available to you to find the structures and the pka of these drugs. Identify the functional groups on each drug that will readily ionize under the appropriate ph conditions. Finally, determine the degree of ionization of the drug at physiological pH (7.4). MDMA Amphetamine Butalbital Hydrocodone Carisoprodol Fentanyl
This question was created from PHA6471 Synthetic Chem Module 1.pdf
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