L. J. is a 55-year-old male who attended a funeral and found...

L. J. is a 55-year-old male who attended a funeral and found himself laughing during the service, but later that evening he was irritated with himself for what he had done. His wife said this was abnormal behavior and took him to his doctor to be evaluated. After L. J.'s MRI was reviewed, he was diagnosed with frontotemporal dementia. Which medication is recommended to help L. J. with his emotional outbursts?

A.

Memantine

B.

Escitalopram

C.

Donepezil

D.

Risperidone

When can buprenorphine be initiated in a patient who is suffering from an opioid overdose?

A.

As soon as the patient is stabilized

B.

It should be administered as soon as you find the patient unconscious

C.

Right after naloxone is administered to prevent the patient from going back into opioid overdose

D.

When the patient is experiencing mild-to-moderate symptoms of withdrawal

Of the following neurotransmitters, which one(s) are known to be severely disrupted in the disease Dementia with Lewy Bodies?

1. Acetylcholine
2. Glutamate
3. Dopamine
4. GABA
5. Norepinephrine

A.

II only

B.

III only

C.

I and II

D.

I and III

Choose the correct statement regarding medications used for alcoholism

A.

Disulfiram: NMDA receptor antagonist & GABAA agonist

B.

Naltrexone: µ-opioid receptor antagonist that reduces the reinforcement/euphoria produced by alcohol

C.

Acamprosate: enhances the effect of the inhibitory neurotransmitter gamma-aminobutyric acid on the GABA receptors by binding to a site that is distinct from the GABA binding site in the central nervous system.

D.

Lorazepam: inhibits alcohol dehydrogenase, leading to a buildup of acetaldehyde

Patient is a 75-year-old female with a confirmed diagnosis of Alzheimer's Disease. She is currently on Donepezil 10 mg daily. She is accompanied to your clinic today by her daughter, who informs you that her mother has recently had an increase in depressive symptoms. She has no history of mood disorders. She has a history of hypertension and tonic-clonic seizures, but both are controlled. Assuming this patient will be thoroughly evaluated for the diagnosis of depression, what would you recommend as initial therapy?

A.

Amitriptyline

B.

Doxepin

C.

Fluoxetine

D.

Bupropion

Which neurotransmitters are likely involved in the pathophysiology of withdrawal seizures?

1. Serotonin
2. Endorphins
3. Glutamate
4. GABA
5. Dopamine

A.

I and II

B.

II and V

C.

I and III

D.

III and IV

Which medication below should be routine for all suspected cases of alcohol intoxication and dependence?

A.

B vitamin thiamine 100 mg

B.

Haloperidol 5 mg

C.

Lorazepam 2 mg

D.

Acamprosate 666 mg

T. C. is an 88-year-old male who is diagnosed at your clinic with Dementia with Lewy Bodies. He currently has some debilitating gait issues, which makes his quality of life very poor. His memory is still intact with minor deficits. Which medication would likely benefit T. C. as his initial therapy?

A.

Levodopa/carbidopa

B.

Galantamine

C.

Memantine

D.

Benztropine

In the pathophysiology of Alzheimer's Disease, there are certain proteins that lead to the plaques and tangles that result in this progressive, irreversible brain disorder. Choose the appropriate protein with its corresponding pathology.

1. Tau - tangles
2. Beta-amyloid - tangles
3. Tau - plaques
4. Beta-amyloid - plaques

A.

I and II

B.

II and III

C.

II and IV

D.

I and IV

T. K. is a 72-year-old female who has suffered many strokes in the past, likely due to uncontrolled hypertension and hyperlipidemia. She has now been diagnosed with vascular dementia due to memory loss and motor system slowing. What is the recommended treatment for T. K.?

A.

T. K. needs the drug donepezil to help with her memory loss only.

B.

T. K. needs the drug donepezil to help with her memory loss, but also needs her hypertension and hyperlipidemia controlled.

C.

T. K. needs the drug donepezil to help with her memory loss, but also needs her hypertension controlled.

D.

T. K. needs her hypertension controlled only.