There are several different guidelines that should be used when designing websites. Which statement is not
Gaming websites is where you cannot assume that the users will have the latest plug-ins and browsers and are quite technologically savvy.
Academic and scientific sites should have additional focus on how the site functions in graphics-free browsing environments.
Consumer audience websites should pay special attention to site performance and presentation.
A controlled environment where a specific browser is being used, as in a corporate environment, is where it is best to use all that the website has to offer. Employees usually attend training to learn how to use these sites and the designer can use the browsers full potential.